Evaluation of furazolidone, sulfadimidine and amprolium to treat coccidiosis in beetal goats under field conditions

Coccidiosis is a protozoal and occasionally fatal diarrheic disease of goats imposing heavy economic losses to farming community. This study aimed to evaluate the efficacies of Furazolidone, Sulfadimidine and Amprolium against coccidiosis in Beetal goats. Twenty-four [24] Beetal goats naturally infected with coccidiosis were randomly divided into four groups of 6 [A-D]. Goats in groups A, B and C were treated orally with Furazolidone [10mg/Kg], Sulfadimidine [100mg/Kg] and Amprolium [55mg/Kg], respectively for 7 days. Goats in-group D served as positive control. Oocysts per gram [OPG] of feces counts of individual goats in each group were performed on Days; 0 [pre-treatment] 7, 14 and 21 [post-treatment]. OPG counts amongst goats in all groups at day 0 were not significant [P>0.05]. On days 7, 14 and 21, OPG values decreased significantly [P<0.05] in groups A, B and C compared to group D. The efficacy of Furazolidone, Sulfadimidine and Amprolium was 98.6, 98.0 and 99.6 percent, respectively on Day 21 [end of trial]. Statistically, the efficacies of three drugs were not significantly different [P>0.05]. In conclusion, Furazolidone, Sulfadimidine and Amprolium are well-tolerated and any one of these may be recommended to effectively treat coccidiosis in Beetal goats

Avaliacao pre-operatoria na cirurgia da otite media cronica / Chronic suppurative otitis media: preoperative evaluation

A otite media cronica supurativa (OMCSup), infeccao do ouvido medio acompanhada de perfuracao timpanica e otorreia ou suas sequelas, e enfermidade frequente, particularmente na populacao mais carente, na qual o tratamento clinico primario pode ser deficiente. Diversas bacterias aerobias e anaerobias participam da infeccao do ouvido medio, principalmente Pseudomonas aeruginosa, Staphylococcus aureus e Bacterioides fragilis. Na OMCSup ativa (com otorreia), nosso tratamento inicial envolve limpeza metodica do conduto auditivo e a associacao de sulfametoxazol 800 mg+ trimetropin 160 mg po bid l4d com gotas otologicas de cloranfenicol e polimixina B. Embora empirica, essa terapeutica permite, com baixo custo, atacar os principais microrganismos, com risco inexpressivo de ototoxicidade. Cultura e antibiogramas da secrecao sao feitos apenas na falencia dessa medicacao, quando a escolha do antibiotico e baseada na bacteria (aerobia) isolada, adicionando-se metronidazol 400 mg po tid l4d, para combater presumiveis anaerobios associados. Apos, o paciente e avaliado quanto a sequelas e necessidade de tratamento cirurgico visando: 1) combater a infeccao e suas recrudescencias; 2) restaurar ou manter a audicao. Rotineiramente, sao feitos testes audiologicos e radiografias de ouvido nas posicoes de Schuller, Stenvers ou Guillen, e transorbitaria antero-posterior. Em casos especiais, podem ser necessarias tomografias lineares, e mesmo computadorizadas axiais-coronais de ouvidos, com janela ossea e para partes moles.